Elevated blood histamine levels and mast cell degranulation in solar urticaria.
نویسندگان
چکیده
منابع مشابه
Mast Cell Degranulation and Histamine Release Observed in a New in Vitro System
A method is described by which mast cells harvested from the rat peritoneal cavity can be deposited on the surface of a Millipore filter without gross injury, permitting observation of morphological and chemical changes induced by a variety of agents. These isolated peritoneal mast cells respond to 48/80 and to polymyxin B but not to dextran or ovomucoid with degranulation and histamine release...
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Cutaneous neurofibroma 1/9/M 0 1.15 ND + + 2/10/M 0 0.62 ND 3/10/F 0 0.99 ND 4/14/M 1–10 1.32 ND 5/24/F 1–10 1.31 ND + + 6/27/M 11–100 0.65 15.6 (T) + + 7/32/M 11–100 0.52 ND 8/35/M 11–100 0.55 ND 9/36/M 101–1000 0.17 85.2 (T) 10/37/F 11–100 0.51 20.4 (H) 11/38/F 101–1000 0.52 ND 12/51/F 101–1000 0.29 10 (E) 13/59/F 11–100 0.41 ND 14/62/F 11–100 0.56 ND 15/63/F 11–100 0.38 ND + 16/66/F 101–1000...
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In mouse mast cells, both Fc e RI and Fc g RIII are abg 2 tetrameric complexes in which different a chains confer IgE or IgG ligand recognition while the signaling FcR b and g chains are identical. We used primarily noninvasive techniques (changes in body temperature, dye extravasation) to assess systemic anaphylactic responses in nonanesthetized wild-type, Fc e RI a chain 2 / 2 and FcR g chain...
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Substance P and other polycationic peptides are thought to stimulate mast cell degranulation via direct activation of G proteins. We investigated the ability of extracellularly applied substance P to translocate into mast cells and the ability of intracellularly applied substance P to stimulate degranulation. In addition, we studied by reverse transcription--PCR whether substance P-specific rec...
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We investigated the mechanism by which inosine, a metabolite of adenosine that accumulates to . 1 mM levels in ischemic tissues, triggers mast cell degranulation. Inosine was found to do the following: ( a ) compete for [ 125 I] N 6 -aminobenzyladenosine binding to recombinant rat A 3 adenosine receptors (A 3 AR) with an IC 50 of 25 6 6 m M; ( b ) not bind to A 1 or A 2A ARs; ( c ) bind to newl...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 1980
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.1980.tb05831.x